BID 2 BEAT AIDS is an annual entertainment memorabilia auction with proceeds going to LIFEbeat, an organisation dedicated to reaching America’s youth with the message of HIV/AIDS prevention. LIFEbeat mobilizes the talents and resources of the music industry to raise awareness and to provide support to the AIDS community.

Founded in 1883, Chabot Space & Science Center is a nonprofit interactive science center whose mission is to inspire and educate students of all ages about Planet Earth and the Universe.
Tom Hanks, who visited Chabot as an Oakland student, is on the Honorary Committee for the Chabot's 125th Anniversary Gala.

The Women's Cancer Research Fund, a program of the Entertainment Industry Foundation, was established by Chairs Rita Wilson, Tom Hanks, Kate Capshaw and Steven Spielberg, along with Founders Kelly Chapman Meyer, Anne Douglas, Quinn Ezralow, Marion Laurie and Jamie Tisch.
The Women's Cancer Research Fund supports innovative research, education, and outreach directed at the development of more effective approaches to the early diagnosis, treatment and prevention of all women's cancers.

Elevate Hope provides abused and abandoned children an alternative method of therapy through music and the arts, and funding special services and programs that assist the needs of these children using these fundamental methods.

Creating a future of hope for children and families worldwide by eradicating pediatric AIDS, providing care and treatment to people with HIV/AIDS, and accelerating the discovery of new treatments for other serious and life-threatening pediatric illnesses.

The world’s largest family of camps for children with serious illnesses and life threatening conditions. More than 100,000 seriously ill children from 34 states and 31 countries have attended the Camps free of charge.
 

Founded in 1998, the Freeplay Foundation is now called Lifeline Energy. The foundation is committed to providing innovative and practical energy solutions and to ensuring sustained access to information and education via radio. The organization donates specially designed wind-up, solar powered radios to remote villages in Africa to provide information and communication.

"The Lifeline radio can change the world - one person, one house, one village at a time. The beauty of the Freeplay Foundation is the technology and the immediacy of its mission: to put radios and lights in the hands of people who need them. Lifeline radios can make a positive impact from the moment they are turned on in one of the villages, and I can think of nothing more noble than helping people light their way." - Tom Hanks -

A unique non-profit organization dedicated to helping children with rare diseases. Through research, education and support the foundation strives to empower people to face the hardships of dealing with rare pediatric diseases.
Tom Hanks is a long-time supporter of the Foundation and member of the Board.

Tom Hanks serves on the Board of Governors of the nonprofit, educational space advocacy organization, dedicated to the creation of a spacefaring civilization.
On April 27, 2000, Tom Hanks received the NASA Public Service Award for his commitment to increasing the public’s interest in space.

Effort by Americans to rally Americans – ONE by ONE – to fight the emergency of global AIDS and extreme poverty.

Raising money to construct a new facility that replaces the USS Arizona Memorial’s current deteriorating and inadequate Museum and Visitor Center at Pearl Harbor, Hawaii. The building has an estimated life of 4 to 9 years.

A non-profit environmental organization dedicated to the protection and enjoyment of the world’s oceans, waves and beaches for all people, through conservation, activism, research and education.

The objective of the fund is to help researchers develop pilot data from feasibility studies to be subsequently used in new research grant proposals leading to new therapies for the treatment of patients with neuroblastoma.

"It was in October of 2000 actor Tom Hanks phoned James, having heard of James' fascination with the Apollo 13 story. A friendship with the Birrell family arose out of that conversation, and Mr Hanks later graciously agreed to sign on as Honorary Patron of the James Fund." (December 2004)

The Parkinson Society Maritime Region is the voice of Maritimers living with Parkinson’s. Based in Canada, their purpose is to ease the burden and find a cure through support services, education, advocacy and research.

WBV is committed to providing treatment for the American veterans and their families. Their goal is to transform the lives of the returning veterans by changing the way people think and talk about Post Traumatic Stress Disorder, while providing ongoing treatment for veterans and their families in addition to funding research.
Tom Hanks has narrated various PSA and in July 2010, he auctioned off his Prius. All proceeds from the auction benefited the foundation.